MD Doctor of Medicine

Introduction: Coronary Artery Bypass Grafting (CABG) is part of the standard treatment for ischemic heart disease. It mainly focuses on the revascularization of the ischemic area by creating alternative routes using arterial or venous grafts. Several pre-, peri-, and post-operative factors contribute to the success of a CABG operation. In terms of postoperative management hemodynamic instability and extubation time play a crucial role. Purpose: The purpose of this study was to compare the duration of mechanical ventilation until the time of extubation, the hemodynamic status, and the length of hospital stay in post-CABG patients. Methodology: The study has the form of a retrospective single-centered cohort study. The data collection was done by reviewing the medical files of ninety-two patients undergone isolated on-pump CABG operation from July 2021 until December 2022 in the cardiac surgery department of Apollonion Private Hospital in Nicosia, Cyprus. After completion of data collection, all the reported variables were subcategorized as pre-, peri- and postoperative. Additionally, the patients involved in the study were further subdivided based on their time of extubation into three groups, “very early,” “early” and “regular/late”. Afterward, bivariate and multiple linear regression analyses were performed in order to assess the relationships between extubation time and specific predictor variables. Results: All the included participants were of advanced age (mean=67.58 years). Additionally, a correlation between cardiopulmonary bypass time and cross-clamp time and an association between postoperative volume balance and CRP were, also, revealed. The hemodynamic status seemed to be unaffected by the timing of extubation as atrial fibrillation and duration of vasopressor use did not have any statistical difference. Conclusion: The extubation time does not influence the postoperative status in terms of hemodynamic instability, postoperative complications, and length of hospitalization.